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PG01037 (dihydrochloride)

CAT: 0804-HY-103408-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-103408-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PG01037 (dihydrochloride) is a potent and selective dopamine D3 receptor antagonist with a Ki of 0.7 nM[1].
CAS Number
675599-62-9
UNSPSC
12352005
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pg01037-dihydrochloride.html
Purity
99.35
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(NC/C=C/CN1CCN(C2=CC=CC(Cl)=C2Cl)CC1)C3=CC=C(C4=NC=CC=C4)C=C3.[H]Cl.[H]Cl
Molecular Formula
C26H28Cl4N4O
Molecular Weight
554.34
References & Citations
[1]Grundt P, et al. Novel heterocyclic trans olefin analogues of N-{4-[4- (2,3-dichlorophenyl) piperazin-1-yl]butyl}arylcarboxamides as selective probes with high affinity for the dopamine D3 receptor. J Med Chem. 2005 Feb 10;48 (3) :839-48.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
D3 Receptor

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