NAADP

CAT: 0804-HY-103317-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-103317-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NAADP, a nucleotide, is a Ca2+-mobilizing second messenger. NAADP is essential for initiation of Ca2+ signaling[1][2].
CAS Number
[5502-96-5]
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/naadp.html
Purity
95.8
Solubility
H2O : 50 mg/mL (ultrasonic; warming)
Smiles
NC1=NC=NC2=C1N=CN2[C@@H]3O[C@H](COP(OP(OC[C@H]4O[C@@H]([N+]5=CC(C(O)=O)=CC=C5)[C@H](O)[C@@H]4O)(O)=O)(O)=O)[C@@H](O)[C@H]3OP(O)([O-])=O
Molecular Formula
C21H27N6O18P3
Molecular Weight
744.39
Precautions
H315, H319, H335
References & Citations
[1]Walseth TF, et al: From Discovery to Mechanism. Front Immunol. 2021 Sep 7;12:703326. |[2]Davis LC, et al. NAADP activates two-pore channels on T cell cytolytic granules to stimulate exocytosis and killing. Curr Biol. 2012 Dec 18;22 (24) :2331-7. |[3]Rah SY, et al. NAADP-mediated Ca2+ signaling promotes autophagy and protects against LPS-induced liver injury. FASEB J. 2017 Jul;31 (7) :3126-3137.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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