CGRP antagonist 4

• UNSPSC Description:

  CGRP antagonist 4 is an antagonist of calcitonin gene-related peptide (CGRP) receptor. CGRP antagonist 4 shows the highest affinity for CGRP receptors in the human brain. CGRP antagonist 4 can be used to study the binding properties of non-peptide calcitonin gene-related peptide (CGRP) receptor antagonist (gepants) in rat, pig and human menes [1].

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/cgrp-antagonist-4.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N(C)C1=CC=CC=C1C)C2=CC=C(S(C3=NC=CS3)=O)C([N+]([O-])=O)=C2

• Molecular Weight:

  401.46

• References & Citations:

  [1]Warfvinge K, et al. The Presence of Calcitonin Gene-Related Peptide and Its Receptors in Rat, Pig and Human Brain: Species Differences in Calcitonin Gene-Related Peptide Pharmacology. Pharmacology. 2019;104(5-6):332-341.

• Shipping Conditions:

  Room temperature

• Storage Conditions:

  Store at room temperature 3 years

• Clinical Information:

  No Development Reported

• CAS Number:

  217438-17-0