IMAC2

• Description :

  IMAC2 is a potent MAC inhibitor with an IC50 of 28 nM and an LD50 of 15000 nM. iMAC2 shows anti-apoptotic effect. iMAC2 blocks cytochrome c release[1].

• UNSPSC :

  12352005

• Target :

  Apoptosis

• Type :

  Reference compound

• Related Pathways :

  Apoptosis

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Cancer; Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/imac2.html

• Solubility :

  10 mM in DMSO

• Smiles :

  FC(CN1CCNCC1)CN2C3=C(C4=C2C=CC(Br)=C4)C=C(Br)C=C3

• Molecular Formula :

  C19H20Br2FN3

• Molecular Weight :

  469.19

• References & Citations :

  [1]Peixoto PM, et al. MAC inhibitors suppress mitochondrial apoptosis. Biochem J. 2009 Oct 12;423 (3) :381-7.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [335166-36-4]