PP7

• UNSPSC Description:

  PP7 is a potent PB1-PB2 interaction inhibitor with an IC50 of 8.6 μM, and their inhibition against viral polymerase activity (IC50=9.5 μM). PP7 shows antiviral activities against influenza A virus (IAV), including A(H1N1)pdm09 (EC50=1.4 μM), A(H7N9) and A(H9N2) subtypes[1].

• Target Antigen:

  Influenza Virus

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/pp7.html

• Solubility:

  10 mM in DMSO

• Smiles:

  ClC1=CC=C(N2C(/C(C(N2)=O)=C/C3=CC=C(OCC)C=C3)=O)C=C1Cl

• Molecular Weight:

  377.22

• References & Citations:

  [1]Yuan S, et al. Identification of a novel small-molecule compound targeting the influenza A virus polymerase PB1-PB2 interface. Antiviral Res. 2017 Jan;137:58-66.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  433238-84-7