cis-ACBD
CAT:
804-HY-100616
Size:
2 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
cis-ACBD
- CAS Number: 73550-55-7
- UNSPSC Description: cis-ACBD is a potent and selective inhibitor of the high-affinity, Na+-dependent plasma membrane glutamate transporter. cis-ACBD is a glutamate reuptake inhibitor. cis-ACBD also acts as linear competitive inhibitor of the uptake of D-[3H]aspartate[1][2].
- Target Antigen: Others
- Type: Reference compound
- Related Pathways: Others
- Applications: Neuroscience-Neuromodulation
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/cis-acbd.html
- Solubility: 10 mM in DMSO
- Smiles: OC([C@]1(C[C@@H](C1)C(O)=O)N)=O
- Molecular Weight: 159.14
- References & Citations: [1]Ai J, et al. Presynaptic excitability as a potential target for the treatment of the traumatic cerebellum. Pharmacology. 2004 Aug;71(4):192-8.|[2]Griffiths R, et al. L-trans-pyrrolidine-2,4-dicarboxylate and cis-1-aminocyclobutane-1,3-dicarboxylate behave as transportable, competitive inhibitors of the high-affinity glutamate transporters. Biochem Pharmacol. 1994 Jan 20;47(2):267-74.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported