Products for Research Use Only
RegisterLogin

CD35 Antibody (Complement Receptor 1)

CAT: 0013-GTR18083203-01Size: 20 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR18083203-01Size:20 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Recognizes a protein of 210-220kDa, which is identified as the Complement receptor 1 or CD35. This mAb is specific for a site in CR1 that is distal from the C3b-binding site, so that it is unable to block CR1/CD35 activity. It is highly specific and shows no cross-reaction with CR2/CD21. The primary function of CR1 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein. Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21+/CD35+/CD1a-. This mAb labels follicular dendritic cells and follicular dendritic cell sarcoma.
UniProt
P17927
Reactivity
Human
Immunogen
Human monocytes were used as the immunogen for this CD35 antibody.
Clonality
Monoclonal
Clone
SPM554
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Purification
Protein G affinity chromatography
Dilution
Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
The optimal dilution of the CD35 antibody for each application should be determined by the researcher.1. Staining of formalin-fixed tissues requires boiling tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min followed by cooling at RT for 20 minutes.2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Tested Applications
IHC-P
Host or Source
Mouse
Preservative
0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin and 0.05% sodium azide
Isotype
Mouse IgG1, kappa

Related Products

CatalogName
GTR17858787Anti-CD35 (complement receptor 1) [8C12]
GTR17858773Anti-CD35 (complement receptor 1) [8C12]
GTR18080948-01CD35 Antibody
GTR18304954CD35 Antibody
GTR17704392CD35 Antibody
GTR17704388CD35 Antibody
GTR18153145CD35 Antibody
GTR18089520-01CD35 Antibody
GTR18572202CD35 Antibody
GTR18580383-01CD35 Antibody

Alternative Products

CatalogName
V4806-20UGCD35 Antibody / Complement receptor 1
V9010IHC-7MLCD35 Antibody (Complement Receptor 1)
V4808SAF-100UGComplement receptor 1 Antibody / CD35
abx133933-01Complement Receptor Type 1 (CD35) Antibody
abx339279-01Complement Receptor Type 1 / CD35 (CR1) Antibody
abx133932-01Complement Receptor Type 1 (CD35) Antibody (PE)
abx415058Complement Receptor Type 1 (CD35) Antibody (RPE)
361573Complement Receptor 1/2 (CD21, CD35)
MBS488174-01Anti-CD35 (complement receptor 1) [8C12]

Popular Products