Products for Research Use Only
RegisterLogin

Recombinant CD162 Antibody

CAT: 0013-GTR18083006-01Size: 20 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR18083006-01Size:20 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CD162 glycoprotein functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response.
UniProt
Q14242
Reactivity
Human
Immunogen
Recombinant full-length human CD162 protein was used as the immunogen for the recombinant CD162 antibody.
Clonality
Recombinant
Clone
RPSGL1/1601
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Purification
Protein G affinity chromatography
Dilution
ELISA: order Ab without BSA for coating
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the recombinant CD162 antibody should be determined by the researcher.
Tested Applications
ELISA
Host or Source
Mouse
Preservative
0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin and 0.05% sodium azide
Isotype
Mouse IgG1, kappa

UniProtKB · Q14242

P-selectin glycoprotein ligand 1

SELPL_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q14242
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SELPLG
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
PSGL-1
EC number
—
Processing
Precursor
Secondary accessions
A8K2Y0, B4DQC3, B7Z5C7, J3KMX6, Q12775, Q6GTW7, Q8N7J7
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Cell adhesionHost-virus interaction

PTM

Cleavage on pair of basic residuesDisulfide bondGlycoproteinPhosphoproteinPyrrolidone carboxylic acidSulfation

Molecular function

Host cell receptor for virus entryReceptor

Cellular component

Membrane

Domain

RepeatSignalTransmembraneTransmembrane helix

Ligand

Sialic acid

Related Products

CatalogName
GTR18153028CD162 Antibody
GTR17857078CD162 Antibody
GTR18152977CD162 Antibody
GTR18711767CD162 Recombinant Mouse mAb Antibody
GTR18408778-01CD162 Recombinant Rabbit mAb
GTR18579389-01CD162 Biosimilar Antibody
GTR18399385-01CD162 polyclonal antibody
GTR17857479CD162 Antibody (FITC)
GTR17856466CD162 Antibody (APC)
GTR18049095-01CD162 polyclonal antibody

Alternative Products

CatalogName
V8394-100UGRecombinant CD162 Antibody
bsm-61840R-TRPSGL-1/CD162 Recombinant Antibody
ENZ-ABS877-0100CD162 recombinant monoclonal antibody (PSGL1/8135R)
bsm-61840R-PE-01PSGL-1/CD162 Recombinant Antibody, PE Conjugated
bsm-61840R-FITC-01PSGL-1/CD162 Recombinant Antibody, FITC Conjugated
bsm-61840R-Cy5-01PSGL-1/CD162 Recombinant Antibody, Cy5 Conjugated
bsm-61840R-PerCP-TRPSGL-1/CD162 Recombinant Antibody, PerCP Conjugated
bsm-61840R-Biotin-TRPSGL-1/CD162 Recombinant Antibody, Biotin Conjugated
AN300442PRecombinant PSGL-1/CD162/SELPLG Monoclonal Antibody
HC298013-01Anti-Human CD162/SELPLG Recombinant Antibody (SAA2392)

Popular Products