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TFF2 Antibody / Trefoil factor 2

CAT: 0013-GTR18082827-01Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18082827-01Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intrachain disulfide bonds, forming the trefoil motif, or P-domain. pS2, also designated Md2, BCEI, TFF1 and pNR-2, is a trefoil protein that is highly expressed in normal gastric mucosa. pS2 has also been detected in a number of carcinomas including cancers of the breast, pancreas and stomach. pS2 is not present in normal breast tissue but is inducible by estrogen in MCF7 cells. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. The gene encoding pS2 maps to human chromosome 21q22.3.
UniProt
Q03403
Reactivity
Human
Immunogen
A synthetic peptide corresponding to a 16-amino acid C-terminal sequence of the human Trefoil factor 2 protein was used as the immunogen for this TFF2 antibody.
Clonality
Monoclonal
Clone
GE16C
Conjugation
Unconjugated
Field of Research
Epigenetics
Purification
PEG precipitation
Dilution
ELISA (order BSA/azide-free format for coating)
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the TFF2 antibody should be determined by the researcher.
Tested Applications
ELISA
Host or Source
Mouse
Preservative
0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin and 0.05% sodium azide
Isotype
Mouse IgM, kappa

UniProtKB · Q03403

Trefoil factor 2

TFF2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q03403
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TFF2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
Q15854
Protein keywords

PTM

Disulfide bond

Technical term

Proteomics identificationReference proteome

Domain

RepeatSignal

Cellular component

Secreted

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