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Cystatin A Antibody / CSTA

CAT: 0013-GTR18082609-01Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18082609-01Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and kininogens. This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. The protein is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Stefins have been proposed as prognostic and diagnostic tools for cancer.
UniProt
P01040
Reactivity
Human
Immunogen
A recombinant human partial protein (amino acids 1-98) was used as the immunogen for the Cystatin A antibody.
Clonality
Monoclonal
Clone
CPTC-CSTA-1
Conjugation
Unconjugated
Field of Research
Epigenetics
Purification
Protein G affinity chromatography
Dilution
Immunohistochemistry (FFPE) : 1-2ug/ml, Western blot: 1-2ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the Cystatin A antibody should be determined by the researcher.
Tested Applications
IHC-P, WB
Host or Source
Mouse
Preservative
0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin and 0.05% sodium azide
Isotype
Mouse IgG2c, kappa

UniProtKB · P01040

Cystatin-A

CYTA_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P01040
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CSTA
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q6IB90
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

Acetylation

Biological process

Cell adhesion

Cellular component

Cytoplasm

Disease

Ichthyosis

Molecular function

Protease inhibitorThiol protease inhibitor

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