Products for Research Use Only
RegisterLogin

ENAH Antibody / MENA

CAT: 0013-GTR18082824-01Size: 20 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR18082824-01Size:20 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
The Wiskott-Aldrich syndrome (WAS) is characterized by thrombocytopenia, eczema, defects in cell-mediated and humoral immunity and a propensity for lymphoproliferative diseases. The syndrome is the result of a mutation in the gene encoding a proline-rich protein termed WASP. WASP is a downstream effector of Cdc42 and has been implicated in actin polymerization and cyto- skeletal organization. Distantly related proteins, VASP (vasodilator-stimulated phosphoprotein) and Mena (for mammalian enabled protein), are involved in the regulation of cytoskeletal dynamics. Both Mena and VASP accumulate at focal adhesions. Mena is highly expressed in the developing nervous system and may be involved in growth cone motility and axon guidance.
UniProt
Q8N8S7
Reactivity
Human
Immunogen
A portion of amino acids 485-589 from the human protein was used as the immunogen for the ENAH antibody.
Clonality
Monoclonal
Clone
ENAH/1988
Conjugation
Unconjugated
Field of Research
Neuroscience
Purification
Protein G affinity chromatography
Dilution
ELISA (order BSA/sodium azide-free format for coating), Western blot: 1-2ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
The stated application concentrations are suggested starting points. Titration of the ENAH antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Tested Applications
ELISA, WB
Host or Source
Mouse
Preservative
0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin and 0.05% sodium azide
Isotype
Mouse IgG2c, kappa

UniProtKB · Q8N8S7

Protein enabled homolog

ENAH_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8N8S7
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ENAH
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
D0PQI2, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Molecular function

Actin-binding

Coding sequence diversity

Alternative splicing

Cellular component

Cell junctionCell projectionCytoplasmCytoskeletonSynapse

Domain

Coiled coilRepeatSH3-binding

PTM

Phosphoprotein

Related Products

CatalogName
GTR18219272-01Rabbit ENAH/MENA Antibody
GTR18219271-01Rabbit ENAH/MENA Antibody
GTR17694843ENAH/MENA Rabbit Polyclonal Antibody
GTR18993498ENAH/MENA Antibody Blocking Peptide
GTR18752178ENAH/MENA Rabbit Polyclonal Antibody (Fluoro488)
GTR18752177ENAH/MENA Rabbit Polyclonal Antibody (Fluoro550)
GTR18546036ENAH/MENA Rabbit Polyclonal Antibody (Cy3)
GTR18546033ENAH/MENA Rabbit Polyclonal Antibody (HRP)
GTR18546032ENAH/MENA Rabbit Polyclonal Antibody (APC)
GTR18546031ENAH/MENA Rabbit Polyclonal Antibody (PE)

Alternative Products

CatalogName
RQ6766MENA Antibody / ENAH
V7474SAF-100UGENAH Antibody / MENA
A05337-1Anti-Mena ENAH Antibody
A05337-2Anti-ENAH/MENA Antibody Picoband®
MBS1755453-01Anti-ENAH/MENA Antibody Picoband
NBP2-79752-100ugMouse Monoclonal Mena Antibody (ENAH/1988)
PAV8877Rabbit Anti-Mena/ENAH Polyclonal Antibody
36-3036-20Anti-ENAH / MENA (Actin Regulator) Monoclonal Antibody (Clone: ENAH/1988)
A05337-2-FITCAnti-ENAH/MENA Antibody Picoband®, FITC Conjugate
A05337-2-Dylight594Anti-ENAH/MENA Antibody Picoband®, Dylight594 Conjugate

Popular Products