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Recombinant TIMP2 Antibody

CAT: 0013-GTR18082591-01Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18082591-01Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TIMP2 is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, Metalloproteinase inhibitor 2 / TIMP2 has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, it may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. [RefSeq]
UniProt
P16035
Reactivity
Human
Immunogen
Amino acids 56-66 (DSGNDIYGNPI) from the human protein were used as the immunogen for this recombinant TIMP2 antibody.
Clonality
Recombinant
Clone
MPIB2-1R
Conjugation
Unconjugated
Field of Research
Epigenetics
Purification
Protein A affinity chromatography
Dilution
Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT, Prediluted IHC only format: incubate for 30 min at RT (1)
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the recombinant TIMP2 antibody should be determined by the researcher.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Tested Applications
IHC-P
Host or Source
Rabbit
Preservative
0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin and 0.05% sodium azide
Isotype
Rabbit IgG, kappa

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