Products for Research Use Only
RegisterLogin

PS2 Antibody / TFF1

CAT: 0013-GTR18082495-01Size: 20 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR18082495-01Size:20 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
It recognizes a polypeptide of 6.5kDa, identified as pS2 estrogen-regulated protein. pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intra-chain disulfide bonds, forming the trefoil motif, or P-domain. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. About 60% of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. It is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract. Several studies have shown that pS2 is primarily expressed in estrogen receptor-positive breast tumors and it may define a subset of estrogen-dependent tumors that displays an increased likelihood of response to endocrine therapy.
UniProt
P04155
Reactivity
Human
Immunogen
Recombinant human protein was used as the immunogen for this pS2 antibody.
Clonality
Monoclonal
Clone
TFF1/2133
Conjugation
Unconjugated
Field of Research
Epigenetics
Purification
Protein G affinity chromatography
Dilution
Flow cytometry: 1-2ug/10^6 cells, Immunofluorescence: 1-2ug/ml, Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
The optimal dilution of the pS2 antibody for each application should be determined by the researcher.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Tested Applications
FACS, IF, IHC-P
Host or Source
Mouse
Preservative
0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin and 0.05% sodium azide
Isotype
Mouse IgG2b, kappa

Related Products

CatalogName
GTR18398378-01TFF1 / pS2 antibody
GTR18297396-01TFF1/pS2 polyclonal antibody
GTR18046600-01TFF1/pS2 polyclonal antibody
GTR18317442PS2 Antibody / Estrogen Inducible Protein pS2 / TFF1
GTR18317443-01PS2 Antibody / Estrogen Inducible Protein pS2 / TFF1
GTR18317408Recombinant pS2 Antibody / Estrogen Inducible Protein pS2 / TFF1
GTR18317409-01Recombinant pS2 Antibody / Estrogen Inducible Protein pS2 / TFF1
GTR18574160TFF1 Antibody / Estrogen Inducible Protein pS2
GTR18082362-01TFF1 Antibody / Estrogen Inducible Protein pS2
GTR18574159TFF1 Antibody / Estrogen Inducible Protein pS2

Alternative Products

CatalogName
70R-14227TFF1 antibody

Popular Products