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Carlinoside

CAT: 0804-HY-125129-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-125129-01Size:1 mg
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Description
Carlinoside is a flavone glycoside with hepatoprotective efficiency. Carlinoside reduces hepatic bilirubin accumulation by stimulating bilirubin-UGT activity through Nrf2 gene expression. Carlinoside has the potential to intervene hyperbilirubinemia due to liver dysfunction[1].
CAS Number
59952-97-5
UNSPSC
12352005
Target
Keap1-Nrf2
Type
Natural Products
Related Pathways
NF-κB
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/carlinoside.html
Solubility
10 mM in DMSO
Smiles
OC1=C([C@@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)CO)C(O)=C(C(C=C(C3=CC(O)=C(O)C=C3)O4)=O)C4=C1[C@H]5[C@@H]([C@H]([C@@H](O)CO5)O)O
Molecular Formula
C26H28O15
Molecular Weight
580.49
References & Citations
[1]Kundu, et al. Carlinoside reduces hepatic bilirubin accumulation by stimulating bilirubin-UGT activity through Nrf2 gene expression. Biochem Pharmacol. 2011 Nov 1;82 (9) :1186-97.|[2]Das S, et al. Impact of edaphic factors and nutrient management on the hepatoprotective efficiency of Carlinoside purified from pigeon pea leaves: An evaluation of UGT1A1 activity in hepatitis induced organelles. Environ Res. 2018 Feb;161:512-523.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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CatalogName
GTR19260780Carlinoside

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