Products for Research Use Only

Keratin 19 Antibody

CAT: 0013-GTR18082342-01Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18082342-01Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cytokeratin 19 is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Cytokeratin 19 is a type I keratin. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically found in the periderm, the transiently superficial layer that envelops the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. [Wiki]
UniProt
P08727
Reactivity
Human
Immunogen
Recombinant human KRT19 protein was used as the immunogen for the Keratin 19 antibody.
Clonality
Monoclonal
Clone
CTKN19-1
Conjugation
Unconjugated
Field of Research
Epigenetics, Infectious Diseases
Purification
Protein G affinity chromatography
Dilution
Western blot: 1-2ug/ml, Flow cytometry: 1-2ug/10^6 cells, Immunofluorescence: 1-2ug/ml, Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT, Prediluted IHC only format: incubate for 30 min at RT (1)
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Titering of the Keratin 19 antibody may be required for optimal performance.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Tested Applications
FACS, IF, IHC-P, WB
Host or Source
Mouse
Preservative
0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin and 0.05% sodium azide
Isotype
Mouse IgG2a, kappa

UniProtKB · P08727

Keratin, type I cytoskeletal 19

K1C19_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P08727
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
KRT19
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B2R874, Q5XG83, Q6NW33, Q7L5M9, Q96A53, Q96FV1, Q9BYF9, Q9P1Y4
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Domain

Coiled coil

Biological process

Host-virus interaction

Cellular component

Intermediate filamentKeratin

PTM

MethylationPhosphoprotein