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AMPD3 Antibody

CAT: 0013-GTR18082237-01Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18082237-01Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AMPD3 is a member of the AMP deaminase gene family. It is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. This gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. Mutations in the gene lead to the clinically asymptomatic, autosomal recessive condition erythrocyte AMP deaminase deficiency. [RefSeq]
UniProt
Q01432
Reactivity
Human
Immunogen
Recombinant full-length human protein was used as the immunogen for the AMPD3 antibody.
Clonality
Monoclonal
Clone
ETAD3-1
Conjugation
Unconjugated
Field of Research
Metabolism Research
Purification
Protein G affinity chromatography
Dilution
Immunohistology (FFPE) : 2-4ug/ml for 30 min at RT (1), Prediluted IHC only format: incubate for 30 min at RT (2)
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the AMPD3 antibody should be determined by the researcher.1. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Tested Applications
IHC-P
Host or Source
Mouse
Preservative
0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin and 0.05% sodium azide
Isotype
Mouse IgG2b, kappa

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