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Linearmycin A

CAT: 0804-HY-N11756Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N11756Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Linearmycin A is a polyene antibiotic that has been found in Streptomyces. It is active against the bacteria S. aureus and E. coli (MICs=3.1 and 1.6 μg/disc, respectively), the fungi S. cerevisiae and C. albicans (MICs=0.1 and 1.6 μg/disc, respectively), and the plant pathogenic fungus A. niger in disc assays (MIC=0.2 μg/disc) . Linearmycin A induces lysis and degradation of B. subtilis as a component of Streptomyces Mg1 extract.
CAS Number
163596-98-3
UNSPSC
12352211
Target
Antibiotic; Bacterial
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/linearmycin-a.html
Smiles
OC(/C(C)=C/C=C/C=C/C=C/CC/C=C/C(C)[C@H](O)[C@@H](C)[C@H](O)/C=C/C=C/C=C/C=C/C=C/CC(O)C(C)C(CC(O)C[C@H](O)C[C@H](O)/C=C/C[C@@H](O)C[C@H](O)C[C@@H](O)C[C@H](O)/C=C/CC(O)/C=C/C[C@H](O)C[C@H](O)CCCN)=O)=O
Molecular Formula
C64H101NO16
Molecular Weight
1140.48
References & Citations
[1]Sakuda, et al. Novel linear polyene antibiotics: Linearmycins. J. Chem. Soc. Perkin 1 18, 2315-2319 (1996) .
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported