NS-11021

CAT: 0026-B2595-25Size: 25 mgDry Ice: NoHazardous: No
CAT#:0026-B2595-25Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NS-11021 is a novel KCa1.1 channel activator. At concentrations above 0.3 μM, activates KCa1.1 in a concentration-dependent manner by parallel-shifting the channel activation curves to more negative potentials. Single-channel analysis reveals that NS-11021 increases the open probability of the channel by altering gating kinetics without affecting the single-channel conductance. NS-11021 (10 μM) influenced neither a number of cloned Kv channels nor endogenous Na+ and Ca²⁺ channels (L- and T-type) in guinea pig cardiac myocytes.
Shipping Conditions
Gel Pack
Storage Conditions
-20ºC
Shelf Life
36 months

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