Products for Research Use Only
RegisterLogin

Double Stranded DNA Antibody

CAT: 0013-GTR18081606-01Size: 20 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR18081606-01Size:20 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
This mAb recognizes the double stranded DNA in human cells. It can be used to stain the nuclei in cell or tissue preparations and can be used as a nuclear marker in human cells. This mAb produces a homogeneous staining pattern in the nucleus of normal and malignant cells. Deoxyribonucleic acid (DNA) is a nucleic acid that stores long-term information regarding the development and function of all known living organisms. DNA consists of two long nucleotide polymers, which are composed of four bases, namely adenine, thymine, guanine and cytosine, all of which are flanked by a phosphate-deoxyribose backbone. Normally, DNA exists as a double-stranded (ds) molecule that forms in the shape of a double helix, allowing the bases and the backbone of the two strands to interact, thus forming a polynucleotide. When the double helix is unwound (either by enzymes or heat), DNA exists as a single-stranded (ss) molecule that is less stable than the double helix, but is necessary for protein access to DNA bases. Double stranded DNA markers are useful tools in biology research and aid in the study of DNA behavior and characteristics.
Reactivity
Human
Immunogen
Nuclei of Burkitt's cells were used as the immunogen for the Double Stranded DNA antibody.
Clonality
Monoclonal
Clone
DSD/958
Conjugation
Unconjugated
Purification
Protein G affinity chromatography
Dilution
Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the Double Stranded DNA antibody should be determined by the researcher.1. Staining of formalin-fixed tissues requires boiling tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min followed by cooling at RT for 20 min.2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Tested Applications
IHC-P
Host or Source
Mouse
Preservative
0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin and 0.05% sodium azide
Isotype
Mouse IgG3, kappa

Related Products

CatalogName
GTR18317179-01DsDNA Antibody / Double Stranded DNA
GTR18317168DsDNA Antibody / Double Stranded DNA
GTR18323087Anti-double stranded DNA IgG
GTR18292529Double Stranded DNA (dsDNA) (Nuclear Marker) Antibody
GTR18193048-01Double Stranded DNA (dsDNA) (Nuclear Marker) Antibody
GTR18192988-01Double Stranded DNA (dsDNA) (Nuclear Marker) Antibody
GTR18293173Double Stranded DNA (dsDNA) (Nuclear Marker) Antibody
GTR18292530Double Stranded DNA (dsDNA) (Nuclear Marker) Antibody
GTR18193009-01Double Stranded DNA (dsDNA) (Nuclear Marker) Antibody
GTR18874416-01Double-Stranded DNA (dsDNA) ELISA Kit

Alternative Products

CatalogName
V3104IHC-7MLDouble Stranded DNA Antibody
V5321-100UGDsDNA Antibody / Double Stranded DNA
V5319SAF-100UGDouble Stranded DNA Antibody / dsDNA
abx023954DNA (Single and Double Stranded) Antibody
abx024167Double-Stranded DNA (dsDNA) Antibody
33-534Double Stranded DNA Antibody [SPM603]
STJ16100690Anti-Double stranded DNA antibody
B2010894Double Stranded DNA Antibody Positive Plasma
MBS016840-01Hamster Double Stranded DNA Antibody ELISA Kit
MBS009155-01Human Double Stranded DNA Antibody ELISA Kit

Popular Products