Puromycin

• Description:

  Puromycin dihydrochloride is the dihydrochloride salt of puromycin. Puromycin is an aminoglycoside antibiotic that inhibits protein synthesis.

• Product Name Alternative:

  CL13900

• UNSPSC:

  12352005

• Hazard Statement:

  H302

• Target:

  Antibiotic; Bacterial; Parasite

• Type:

  Natural Products

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/Puromycin.html

• Purity:

  99.55

• Solubility:

  DMSO : 100 mg/mL (ultrasonic) |H2O : 1 mg/mL (ultrasonic)

• Smiles:

  OC[C@@H]1[C@@H](NC([C@@H](N)CC2=CC=C(OC)C=C2)=O)[C@H]([C@H](N3C=NC4=C3N=CN=C4N(C)C)O1)O

• Molecular Formula:

  C22H29N7O5

• Molecular Weight:

  471.51

• Precautions:

  H302

• References & Citations:

  [1]Nathans D, et al. Puromycin inhibition of protein synthesis: incorporation of puromycin intopeptide chains. Proc Natl Acad Sci U S A. 1964 Apr;51:585-92.|[2]Miyamoto-Sato E, et al. Specific bonding of puromycin to full-length protein at the C-terminus. Nucleic Acids Res. 2000 Mar 1;28 (5) :1176-82.|[3]Schmidt EK, et al. SUnSET, a nonradioactive method to monitor protein synthesis. Nat Methods. 2009 Apr;6 (4) :275-7.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  Natural Products

• Clinical Information:

  Launched

• Isoform:

  Aminoglycoside

• Citation 01:

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• CAS Number:

  [53-79-2]