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Tolazamide

CAT: 0572-TRC-T534500-250MGSize: 250 mgDry Ice: NoHazardous: No
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CAT#:0572-TRC-T534500-250MGSize:250 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1156-19-0
Synonyms
Benzenesulfonamide, N-[[(hexahydro-1H-azepin-1-yl)amino]carbonyl]-4-methyl-; Urea, 1-(hexahydro-1H-azepin-1-yl)-3-(p-tolylsulfonyl)- (6CI,7CI,8CI); 1-(4-Methylphenylsulfonyl)-3-(hexahydro-1H-azepin-1-yl)urea; 1-(Hexahydro-1-azepinyl)-3-p-tolylsulfonylurea; 1-(Hexahydro-1H-azepin-1-yl)-3-(p-tolylsulfonyl)urea; Diabewas; N-(p-Toluenesulfonyl)-N'-hexamethyleniminourea; NSC 70762; Norglycin; Tolanase; Tolazamide; Tolinase; U 17835; Tolbutamide Impurity C
Hazard Statement
May cause an allergic skin reaction
Purity
>95% (HPLC)
Smiles
Cc1ccc(cc1)S(=O)(=O)NC(=O)NN2CCCCCC2
Molecular Formula
C14 H21 N3 O3 S
Molecular Weight
311.4
InChI
InChI=1S/C14H21N3O3S/c1-12-6-8-13(9-7-12)21(19,20)16-14(18)15-17-10-4-2-3-5-11-17/h6-9H,2-5,10-11H2,1H3,(H2,15,16,18)
Additionnal Information
IUPAC name: 1-(azepan-1-yl)-3-(4-methylphenyl)sulfonylurea
Shipping Conditions
Room Temperature
Storage Conditions
+4°C

Chemical Information

Tolazamide

Tolazamide is an N-sulfonylurea that is 1-tosylurea in which a hydrogen attached to the nitrogen at position 3 is replaced by an azepan-1-yl group. A hypoglycemic agent, it is used for the treatment of type 2 diabetes mellitus. It has a role as a hypoglycemic agent and a potassium channel blocker.

CAS Number1156-19-0
PubChem CID5503
IUPAC Name1-(azepan-1-yl)-3-(4-methylphenyl)sulfonylurea
Molecular FormulaC14H21N3O3S
Molecular Weight311.40
XLogP1.5
Topological Polar Surface Area86.9
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Heavy Atom Count21
Formal Charge0
Complexity431
SMILES
CC1=CC=C(C=C1)S(=O)(=O)NC(=O)NN2CCCCCC2
InChI
InChI=1S/C14H21N3O3S/c1-12-6-8-13(9-7-12)21(19,20)16-14(18)15-17-10-4-2-3-5-11-17/h6-9H,2-5,10-11H2,1H3,(H2,15,16,18)
InChIKey
OUDSBRTVNLOZBN-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Tolazamide
CAS: 1156-19-0
CID: 5503
Formula: C14H21N3O3S
MW: 311.40
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight311.40
XLogP31.5
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Exact Mass311.13036271
Monoisotopic Mass311.13036271
Topological Polar Surface Area86.9 Ų
Heavy Atom Count21
Formal Charge0
Complexity431
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
T1333-01Tolazamide
A18140-100Tolazamide 100mg
A18140-25Tolazamide 25mg
HY-B0920R-01Tolazamide (Standard)
A18140-10Tolazamide 10mg
A18140-2Tolazamide 2mg
A18140-200Tolazamide 200mg
A18140-5Tolazamide 5mg
A18140-50Tolazamide 50mg
A18140-10mM-DTolazamide 10mM * 1mL in DMSO

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