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CLEC1 Antibody

CAT: 0013-GTR18080811-01Size: 25 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18080811-01Size:25 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CLEC1 is a C-type lectin receptor and part of the ‘Dectin-1 cluster’ subfamily which also includes Dectin-1, LOX-1, CLEC-2, MICL, CLEC12B, and CLEC9A. Similar to other family members, CLEC1 displays N-liked glycosylation and dimerization characteristics, and is found on dendritic cells, monocytes and granulocytes. However, unlike other family members, CLEC1 expression level is upregulated by IL-10 and TGFb, but not by pro-inflammatory stimuli, and it is expressed on endothelial cells. Enhanced expression at allograft sites suggests CLEC1 may have an immune-regulatory function and may support allograft tolerance.
Reactivity
Human
Immunogen
A recombinant protein fragment from the N-terminal portin of human CLEC1 was used as the immunogen for this antibody.
Clonality
Polyclonal
Conjugation
Unconjugated
Purification
Protein A purified antibody
Dilution
Western blot: 2-5ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Provided assay concentrations are suggestions only, CLEC1 antibody titration may be required for optimal results.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.5 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin, 0.05% sodium azide
Isotype
Rabbit IgG

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