Polycarbophil

CAT: 0804-HY-154659-01Size: 250 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-154659-01Size:250 mg

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Description

Polycarbophil is an orally active hydrophilic polymer. Polycarbophil achieves bioadhesion through hydrogen bonding between carboxyl groups and mucosal surfaces, and prolongs compound retention time and regulates compound release through swelling properties. Polycarbophil relieves constipation and diarrhea[1][2][3].

CAS Number

9003-97-8

UNSPSC

12352100

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/polycarbophil.html

Solubility

10 mM in DMSO

Smiles

[Polycarbophil]

References & Citations

[1]Zhu Z, et al. The development of polycarbophil as a bioadhesive material in pharmacy. asian journal of pharmaceutical sciences, 2013, 8 (4) : 218-227.|[2]Grabnar I, et al. Influence of chitosan and polycarbophil on permeation of a model hydrophilic drug into the urinary bladder wall. Int J Pharm. 2003 Apr 30;256 (1-2) :167-73. |[3]Saito T, et al. Laxative and anti-diarrheal activity of polycarbophil in mice and rats. Jpn J Pharmacol. 2002 Jun;89 (2) :133-41.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 2

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Polycarbophil

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