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Nav1.7 Antibody

CAT: 0013-GTR18080480Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18080480Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mouse Anti-Human Nav1.7 Monoclonal IgG1
Product Name Alternative
Nav1.7, SCN9A, ETHA, hNE Na, NE NA, PN1, Voltage gated sodium channel subunit alpha Nav1, Peripheral sodium channel 1, Neuroendocrine sodium channel
UniProt
Q15858
Reactivity
Hamster, Human, Mouse, Rat
Immunogen
Fusion protein amino acids 1751-1946 (C-terminus) of human Nav1.7
Target
Nav1.7
Clonality
Monoclonal
Clone
N68/6 (Formerly sold as S68-6)
Conjugation
Unconjugated
Field of Research
Cancer Biology, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction
Purification
Protein G Purified
Concentration
1 mg/ml
Dilution
WB (1:1000), IHC-P (1:1000), ICC/IF (1:100)
Molecular Weight
230kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
1 μg/ml was sufficient for detection of Nav1.7 in 10 μg of HEK-293 cell lysate transiently expressing Nav1.7 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Tested Applications
AM, ICC, IF, IHC, IP, WB
NCBI Accession Number
NP_002968.1
Host or Source
Mouse
Preservative
PBS pH 7.4, 50% glycerol, 0.09% sodium azide. Storage buffer changes when conjugated.
Isotype
IgG1
Entrez
6335

UniProtKB · Q15858

Sodium channel protein type 9 subunit alpha

SCN9A_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q15858
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SCN9A
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A1BUH5, Q6B4R9, Q6B4S0, Q6B4S1, Q70HX1, Q70HX2, Q8WTU1, Q8WWN4
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneCell projectionMembrane

Disease

Disease variantEpilepsy

PTM

Disulfide bondGlycoproteinPhosphoproteinUbl conjugation

Molecular function

Ion channelSodium channelVoltage-gated channel

Biological process

Ion transportSodium transportTransport

Domain

RepeatTransmembraneTransmembrane helix

Ligand

Sodium

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