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UBP296

CAT: 0804-HY-107605-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-107605-01Size:5 mg
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Description
UBP296 is a potent and selective antagonist of GLUK5-containing kainate receptor in the spinal cord. UBP296 reversibly blocks ATPA-induced depressions of synaptic transmission, and affects AMPA receptor-mediated synaptic transmission directly in rat hippocampal slices[1].
CAS Number
745055-86-1
UNSPSC
12352005
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ubp296.html
Solubility
10 mM in DMSO
Smiles
O=C(N(C=CC1=O)CC(N)C(O)=O)N1CC2=C(C=CC=C2)C(O)=O
Molecular Formula
C15H15N3O6
Molecular Weight
333.30
References & Citations
[1]More JC, et al. Characterisation of UBP296: a novel, potent and selective kainate receptor antagonist. Neuropharmacology. 2004 Jul;47 (1) :46-64.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AMPA Receptor; Kainate Receptor

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