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PIGZ rabbit pAb

CAT: 0855-ES14109-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES14109-01Size:50 µL
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Background
The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells that serves to anchor proteins to the cell surface. This gene encodes a protein that is localized to the endoplasmic reticulum, and is involved in GPI anchor biosynthesis. As shown for the yeast homolog, which is a member of a family of dolichol-phosphate-mannose (Dol-P-Man) -dependent mannosyltransferases, this protein can also add a side-branching fourth mannose to GPI precursors during the assembly of GPI anchors. [provided by RefSeq, Jul 2008]
Description
The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells that serves to anchor proteins to the cell surface. This gene encodes a protein that is localized to the endoplasmic reticulum, and is involved in GPI anchor biosynthesis. As shown for the yeast homolog, which is a member of a family of dolichol-phosphate-mannose (Dol-P-Man)-dependent mannosyltransferases, this protein can also add a side-branching fourth mannose to GPI precursors during the assembly of GPI anchors. [provided by RefSeq, Jul 2008],
UniProt
Q86VD9
Swiss Prot
Q86VD9
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human PIGZ AA range: 251-301
Target
PIGZ
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
Gene ID (Human)
80235

UniProtKB · Q86VD9

GPI alpha-1,2-mannosyltransferase 4

PIGZ_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q86VD9
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PIGZ
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.4.1.-
Processing
—
Secondary accessions
Q9H9G6
Protein keywords

Cellular component

Endoplasmic reticulumMembrane

Molecular function

GlycosyltransferaseTransferase

Biological process

GPI-anchor biosynthesis

Technical term

Proteomics identificationReference proteome

Domain

TransmembraneTransmembrane helix

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