CDC5L Antibody
CAT:
800-V5121SAF-100UG
Size:
100 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
CDC5L Antibody
- Description: Cdc5L (cell division cycle 5-like protein, pombe Cdc5-related protein) is a DNA-binding protein encoded by the human gene CDC5L. Cdc5L contains two HTH Myb-type DNA-binding domains and may shuttle between cytoplasm and nucleus. It is involved in cell cycle control and may act as a transcription activator. Cdc5L is a spliceosomal protein that is highly conserved across species. It belongs to the group of proteins that comprise the core of spliceosomal complexes and are essential for pre-mRNA splicing. Cdc5L is involved in the second catalytic step of pre-mRNA splicing, which involves cleavage at the 3' splice site and the ligation of the exons. This process releases the intact intron lariat. A chromosomal aberration involving Cdc5L is found in multicystic renal dysplasia. This aberration is caused by a translocation (t 6;19,p21;q13.1) with USF-2.
- CAS Number: 9007-83-4
- UniProt: Q99459
- Host: Mouse
- Immunogen: A recombinant partial protein sequence (within amino acids 1-148) from the human protein was used as the immunogen for the CDC5L antibody.
- Clonality: Monoclonal
- Isotype: IgG2a κ
- Applications: FACS, IHC-P
- Format: Purified
- Buffer: 1 mg/ml in 1X PBS; BSA free, sodium azide free
- Reconstitution: Aliquot the CDC5L antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
- Limitations: This CDC5L antibody is available for research use only.