Uroplakin 1B Recombinant Antibody / UPK1B

Uroplakin 1B Recombinant Antibody / UPK1B

• Description: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. UPK1B is expressed by terminally differentiated urothelial cells.
• CAS Number: 9000-83-3
• UniProt: O75841
• Host: Rabbit
• Immunogen: A recombinant partial protein sequence (within amino acids 109-229) from the human protein was used as the immunogen for the UPK1B antibody.
• Clonality: Monoclonal
• Isotype: IgG κ
• Type: Recombinant
• Applications: IHC-P
• Format: Purified
• Buffer: 1 mg/ml in 1X PBS; BSA free, sodium azide free
• Reconstitution: Aliquot the UPK1B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
• Limitations: This UPK1B antibody is available for research use only.