CD26 Antibody

CD26 Antibody

• Description: Recognizes a glycoprotein of 110kDa, identified as CD26 (Workshop VI; Code: N-L039). It is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection. Cross-linking of CD26 using this antibody dramatically enhances the anti-CD3-induced IL-2 production. In Western blotting, this mAb reacts with only glycosylated CD26, but not with the deglycosylated form. It does not prevent ADA binding to CD26.
• CAS Number: 9007-83-4
• UniProt: P27487
• Host: Mouse
• Immunogen: A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the CD26 antibody.
• Clonality: Monoclonal
• Isotype: IgG2a κ
• Applications: WB, IHC-P
• Format: Purified
• Buffer: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
• Reconstitution: Aliquot the CD26 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
• Limitations: This CD26 antibody is available for research use only.