LAMP5 Antibody / Lysosome-Associated Membrane Glycoprotein 5

• Description:

  Lysosome-associated membrane proteins (LAMP) are glycosylated type I membrane proteins that play a role in the biogenesis of the pigment melanin. LAMP-5, also known as C20orf103, is a 280 amino acid protein that belongs to the LAMP family and is mainly found in cytoplasmic vesicles of the neuronal cell body. LAMP-5 is up-regulated upon CpG activation and down-regulated up Toll-like receptor (TLR) ligands.

• Specifications:

  Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT

• UniProt:

  Q9UJQ1

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  Recombinant full-length human LAMP5 protein was used as the immunogen for the LAMP5 antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG2 κ

• Clone:

  LAMP5/7642

• Applications:

  WB, IHC-P

• Purity:

  Protein A/G affinity

• Format:

  Purified

• Buffer:

  0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

• Reconstitution:

  Aliquot the LAMP5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This LAMP5 antibody is available for research use only.

• Storage Conditions:

  Aliquot the LAMP5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

• Applications Notes:

  Optimal dilution of the LAMP5 antibody should be determined by the researcher.

• CAS Number:

  9007-83-4

• Location:

  Cell Surface, Lysosome

• Image Legend:

  Western blot testing of human U937 cell lysate with LAMP5 antibody (clone LAMP5/7642) . Predicted molecular weight ~31 kDa, but may be observed at higher molecular weights due to glycosylation.