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Recombinant CD48 Antibody

CAT: 0800-V4742SAF-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-V4742SAF-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Reacts with human CD48, a 45kDa glycosyl phophatidyl-inositol (GPI) -anchored cell surface protein. CD48 is strongly expressed on lymphocytes and monocytes and weakly on granulocytes but is absent on platelets, fibroblasts, epithelium and endothelium. CD48 is one of marker for detecting the defects of GPI anchoring structure on the patients with paroxysmal nocturnal hemoglobulinuria (PNH) and serves as a low affinity ligand for CD2.
CAS Number
9000-83-3
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT, Western blot: 2-4 µg/mL
UniProt
P09326
Host
Mouse
Reactivity
Human
Immunogen
A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the recombinant CD48 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG1 k
Clone
RCD48/8676
Type
Recombinant
Applications
IHC-P, WB
Purity
Protein A/G affinity
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Aliquot the recombinant CD48 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This recombinant CD48 antibody is available for research use only.
Storage Conditions
Aliquot the recombinant CD48 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the recombinant CD48 antibody should be determined by the researcher.
Location
Cell surface
Image Legend
Western blot testing of human Raji cell lysate with recombinant CD48 antibody. Predicted molecular weight: 28-50 kDa depending on glycosylation level.

UniProtKB · P09326

CD48 antigen

CD48_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P09326
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CD48
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
Q5U055, Q8MGR0
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneMembraneSecreted

PTM

Disulfide bondGlycoproteinGPI-anchorLipoprotein

Domain

Immunoglobulin domainRepeatSignal

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