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S100A4 Antibody

CAT: 0800-V4711SAF-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-V4711SAF-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
S100A4 belongs to the S100 super-family of proteins containing 2 EF-hand calcium-binding domains. S100 genes include at least 25 members, including S100A1-S100A18, trichohyalin, filaggrin, repetin, S100P, and S100Z. S100A4 exerts its function via direct interaction with a number of proteins including P53, P63, non-muscle myosin IIA, Alpha6Beta4 integrin, and liprin b1. S100A4 is overexpressed in highly metastatic cancers, which makes it useful as a marker of tumor progression.
CAS Number
9007-83-4
Specifications
ELISA (Order BSA-free format for coating), Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT
UniProt
P26447
Host
Mouse
Reactivity
Human
Immunogen
A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the S100A4 antibody.
Clonality
Monoclonal
Isotype
IgG2 κ
Clone
S100A4/7097
Applications
ELISA, IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Aliquot the S100A4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This S100A4 antibody is available for research use only.
Storage Conditions
Aliquot the S100A4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the S100A4 antibody should be determined by the researcher.
Location
Nucleus, Cytoplasm
Image Legend
IHC staining of FFPE human spleen tissue with S100A4 antibody (clone S100A4/7097) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

UniProtKB · P26447

Protein S100-A4

S10A4_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P26447
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
S100A4
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A8K7R8, D3DV46, Q6ICP8
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

Acetylation

Ligand

CalciumMetal-binding

Cellular component

CytoplasmNucleusSecreted

Domain

Repeat
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