CD79b Antibody

• Description:

  CD79 (also designated Ig Alpha/Ig beta) is a heterodimer composed of Alpha chains, designated CD79A or MB-1, and beta chains, designated CD79B or B29. The B cell antigen receptor complex (BCR) is formed by the association of CD79 with a membrane immunoglobulin, such as IgM or IgD. The membrane immunoglobulins IgM and IgD achieve surface expression and antigen presentation function in response to CD79 association. The cytoplasmic tails of both CD79A and CD79B contain an ITAM (immuno-receptor tyrosine-based activation) motif, which acts to initiate the BCR signaling reactions by binding to and activating tyrosine kinases.

• Specifications:

  ELISA: 2-4 mg/mL for coating (order BSA-free format), Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT

• UniProt:

  P40259

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  A recombinant fragment of human CD79b protein was used as the immunogen for the CD79b antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG1 k

• Clone:

  CD79b/4960

• Applications:

  ELISA, IHC-P

• Purity:

  Protein A/G affinity

• Format:

  Purified

• Buffer:

  1 mg/ml in 1X PBS; BSA free, sodium azide free

• Reconstitution:

  Aliquot the CD79b antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This CD79b antibody is available for research use only.

• Storage Conditions:

  Aliquot the CD79b antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  1 mg/mL in 1X PBS; BSA free, sodium azide free

• Applications Notes:

  Optimal dilution of the CD79b antibody should be determined by the researcher.

• CAS Number:

  9007-83-4

• Location:

  Cell Surface

• Image Legend:

  IHC staining of FFPE human tonsil tissue with CD79b antibody (clone CD79b/4960) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.