Thrombospondin Antibody / THBS1

Thrombospondin Antibody / THBS1

• Description: The thrombospondin proteins (TSP 1-4) compose a family of glycoproteins that are involved in cell-to-cell and cell-to-matrix signaling. These extracellular, cell surface proteins form complexes of both homo- and heteromultimers. Thrombospondins play a role in development, aggregation of platelets, adhesion and migration of cells, and progression of cells through the growth cycle. Thrombospondin 1 is released from platelets in response to Thrombin stimulation and is a transient component of the extracellular matrix of developing and repairing tissues. Thrombospondin 2 shares a high degree of homology with Thrombospondin 1 and is thought to have overlapping but unique functions. Thrombospondin 3 is a developmentally regulated heparin binding protein. Thrombospondin 4 is neuronally expressed and stimulates neurite outgrowth.
• CAS Number: 9007-83-4
• UniProt: P07996
• Host: Mouse
• Immunogen: A recombinant partial protein sequence (within amino acids 200-400) from the human protein was used as the immunogen for the Thrombospondin-1 antibody.
• Clonality: Monoclonal
• Isotype: IgG1 κ
• Applications: ELISA, IHC-P
• Format: Purified
• Buffer: 1 mg/ml in 1X PBS; BSA free, sodium azide free
• Reconstitution: Aliquot the Thrombospondin-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
• Limitations: This Thrombospondin-1 antibody is available for research use only.