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CD163L1 Antibody

CAT: 0800-V4254SAF-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-V4254SAF-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CD163L1 (CD163 molecule-like 1), also known as scavenger receptor cysteinerich type 1 protein M160 or CD163B, is a 1,453 amino acid protein that belongs to the scavenger receptor cysteine-rich (SRCR) superfamily. Members of the SRCR family contain SRCR domains which are used to influence ligand binding and protein-protein interaction, and are found in cells of the immune system where they exist as membrane-anchored or secreted proteins. Containing 12 SRCR domains, CD163L1 undergoes alternative splicing events to produce 3 isoforms. CD163L1 isoforms 1 and 2 are single-pass type I membrane proteins, unlike isoform 3, which is a secreted protein. CD163L1 isoform 1 is abundantly expressed in lymph node, spleen, thymus and fetal liver, and isoform 2 is found exclusively in spleen. The gene encoding CD163L1 maps to human chromosome 12p13.31.
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT
UniProt
Q9NR16
Host
Mouse
Reactivity
Human
Immunogen
A recombinant fragment of human CD163L1 protein was used as the immunogen for the CD163L1 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
CD163L1/7971
Applications
IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Aliquot the CD163L1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This CD163L1 antibody is available for research use only.
Storage Conditions
Aliquot the CD163L1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the CD163L1 antibody should be determined by the researcher.
Location
Cytoplasm
Image Legend
IHC staining of FFPE human lymph node tissue with CD163L1 antibody (clone CD163L1/7971) . Inset: PBS used in place of primary Ab (secondary Ab negative control) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

UniProtKB · Q9NR16

Scavenger receptor cysteine-rich type 1 protein M160

C163B_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9NR16
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CD163L1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B4E0G7, C9JHR7, E7EVK4, Q2M3B7, Q6UWC2
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneMembraneSecreted

PTM

Disulfide bondGlycoprotein

Domain

RepeatSignalTransmembraneTransmembrane helix

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MBS9629242-01CD163L1 Antibody
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NBP3-24185BMouse Monoclonal CD163L1 Antibody (CD163L1/7972) [Biotin]
NBP3-24185APCMouse Monoclonal CD163L1 Antibody (CD163L1/7972) [Allophycocyanin]
NBP3-24337APCMouse Monoclonal CD163L1 Antibody (CD163L1/7974) [Allophycocyanin]
NBP3-24128HMouse Monoclonal CD163L1 Antibody (CD163L1/7971) [HRP]
NBP3-24128PEMouse Monoclonal CD163L1 Antibody (CD163L1/7971) [PE]
NBP3-24337FMouse Monoclonal CD163L1 Antibody (CD163L1/7974) [FITC]

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