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CD163L1 Antibody

CAT: 0800-V4247-20UGSize: 20 µgDry Ice: NoHazardous: No
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CAT#:0800-V4247-20UGSize:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CD163L1 (CD163 molecule-like 1), also known as scavenger receptor cysteinerich type 1 protein M160 or CD163B, is a 1,453 amino acid protein that belongs to the scavenger receptor cysteine-rich (SRCR) superfamily. Members of the SRCR family contain SRCR domains which are used to influence ligand binding and protein-protein interaction, and are found in cells of the immune system where they exist as membrane-anchored or secreted proteins. Containing 12 SRCR domains, CD163L1 undergoes alternative splicing events to produce 3 isoforms. CD163L1 isoforms 1 and 2 are single-pass type I membrane proteins, unlike isoform 3, which is a secreted protein. CD163L1 isoform 1 is abundantly expressed in lymph node, spleen, thymus and fetal liver, and isoform 2 is found exclusively in spleen. The gene encoding CD163L1 maps to human chromosome 12p13.31.
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT
UniProt
Q9NR16
Host
Mouse
Reactivity
Human
Immunogen
A recombinant fragment of human CD163L1 protein was used as the immunogen for the CD163L1 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
CD163L1/7974
Applications
IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the CD163L1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This CD163L1 antibody is available for research use only.
Storage Conditions
Aliquot the CD163L1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the CD163L1 antibody should be determined by the researcher.
Location
Cytoplasm
Image Legend
IHC staining of FFPE human spleen tissue with CD163L1 antibody (clone CD163L1/7974) . Inset: PBS used in place of primary Ab (secondary Ab negative control) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
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