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Mammaglobin Antibody

CAT: 0800-V4171SAF-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-V4171SAF-100UGSize:100 µg
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Description
Mammaglobin, 10 kDa, is a cytoplasmic protein, a mammary-specific member of the uteroglobin family. It is related to a family of epithelial secretory proteins that includes prostatein and Clara cell protein.Mammaglobin occurs in about 80% of breast carcinomas. The extend is generally larger than that of GCDFP-15. Up to 15% of nonbreast carcinomas (such as stomach, lung, colon, hepatobiliary, thyroid, ovarian, and urothelial carcinomas) have been reported positive, usually only focally. Mammaglobin is a sensitive and fairly specific marker for breast carcinoma. The panel should also include Gross cystic disease fluid protein-15 and Estrogen receptor alpha.
CAS Number
9000-83-3
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT
UniProt
Q13296
Host
Rabbit
Reactivity
Human
Immunogen
A recombinant fragment of human Mammaglobin/SCGB2A2 protein was used as the immunogen for the Mammaglobin antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG κ
Clone
MGB/7980R
Type
Recombinant
Applications
IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Aliquot the Mammaglobin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Mammaglobin antibody is available for research use only.
Storage Conditions
Aliquot the Mammaglobin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the Mammaglobin antibody should be determined by the researcher.
Location
Cytoplasm
Image Legend
IHC staining of FFPE human lactating breast tissue with Mammaglobin antibody (clone MGB/7980R) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

UniProtKB · Q13296

Mammaglobin-A

SG2A2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q13296
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SCGB2A2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
A1A522, Q86WH8
Protein keywords

Coding sequence diversity

Alternative splicing

PTM

Glycoprotein

Technical term

Proteomics identificationReference proteome

Cellular component

Secreted

Domain

Signal
Product Datasheet
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