Products for Research Use Only

SLC18A2 Antibody / VMAT2

CAT: 0800-V4123SAF-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-V4123SAF-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Neurotransmission depends on the regulated exocytotic release of chemical transmitter molecules. This requires the packaging of these substances into the specialized secretory vesicles of neurons and neuroendocrine cells, a process mediated by specific vesicular transporters. The family of genes encoding the vesicular transporters of monoamines (VMAT 1 and VMAT 2) and acetylcholine (VACht) have been cloned and functionally characterized. The sequence of these integral membrane proteins predicts twelve transmembrane domains and weak homology to a class of bacterial antibiotic resistance proteins. The vesicular transport of neurotransmitter molecules has been shown to be an active ATP- and proton dependent transport mechanism.
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT
UniProt
Q05940
Host
Mouse
Reactivity
Human
Immunogen
A recombinant fragment of human SLC18A2 protein was used as the immunogen for the SLC18A2 antibody.
Clonality
Monoclonal
Isotype
IgG2 κ
Clone
SLC18A2/7983
Applications
IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Aliquot the SLC18A2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This SLC18A2 antibody is available for research use only.
Storage Conditions
Aliquot the SLC18A2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the SLC18A2 antibody should be determined by the researcher.
Location
Cytoplasm
Image Legend
IHC staining of FFPE human brain tissue with SLC18A2 antibody (clone SLC18A2/7983) . Inset: PBS used in place of primary Ab (secondary Ab negative control) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.