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PTEN Antibody

CAT: 0800-V4110-20UGSize: 20 µgDry Ice: NoHazardous: No
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CAT#:0800-V4110-20UGSize:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PTEN (phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase) contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. It was identified as a tumor suppressor that is mutated in a large number of cancers, including sporadic brain, breast, kidney, and prostate cancers.
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT
UniProt
P60484
Host
Mouse
Reactivity
Human
Immunogen
Recombinant full-length human PTEN protein was used as the immunogen for the PTEN antibody.
Clonality
Monoclonal
Isotype
IgG κ
Clone
PTEN/7344
Applications
IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the PTEN antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This PTEN antibody is available for research use only.
Storage Conditions
Aliquot the PTEN antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the PTEN antibody should be determined by the researcher.
Location
Cytoplasm, Nucleus
Image Legend
IHC staining of FFPE human prostate carcinoma tissue with PTEN antibody (clone PTEN/7344) at 2ug/ml. Inset: PBS used in place of primary Ab (secondary Ab negative control) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

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