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SCO1 Antibody

CAT: 0800-RQ7435Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ7435Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Protein SCO1 homolog, mitochondrial, also known as SCO1, cytochrome c oxidase assembly protein, is a protein that in humans is encoded by the SCO1 gene. Mammalian cytochrome c oxidase (COX) catalyzes the transfer of reducing equivalents from cytochrome c to molecular oxygen and pumps protons across the inner mitochondrial membrane. In yeast, 2 related COX assembly genes, SCO1 and SCO2 (synthesis of cytochrome c oxidase), enable subunits 1 and 2 to be incorporated into the holoprotein. This gene is the human homolog to the yeast SCO1 gene.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Flow cytometry: 1-3ug/million cells, Immunofluorescence: 5 µg/mL, Direct ELISA: 0.1-0.5 µg/mL
UniProt
O75880
Host
Rabbit
Reactivity
Human
Immunogen
E. coli-derived recombinant human protein (amino acids R21-S301) was used as the immunogen for the SCO1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, FACS, IF, Direct ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the SCO1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This SCO1 antibody is available for research use only.
Storage Conditions
After reconstitution, the SCO1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the SCO1 antibody should be determined by the researcher.
Location
Cytoplasmic (mitochondria)
Image Legend
Immunofluorescent staining of FFPE human intestine cancer tissue with SCO1 antibody (red) and DAPI nuclear stain (blue) . HIER: steam section in pH8 EDTA buffer for 20 min.

UniProtKB · O75880

Cytochrome c oxidase assembly factor SCO1

SCO1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O75880
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SCO1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B2RDM0
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Molecular function

Chaperone

Ligand

CopperMetal-binding

Biological process

Cytochrome c-type biogenesis

Disease

Disease variantPrimary mitochondrial disease

PTM

Disulfide bond

Cellular component

MembraneMitochondrionMitochondrion inner membrane

Domain

Transit peptideTransmembraneTransmembrane helix

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