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CCDC115 Antibody

CAT: 0800-RQ7155Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ7155Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Coiled-coil domain containing 115 is a protein that in humans is encoded by the CCDC115 gene. The protein encoded by this gene has been observed to localize to the endoplasmic reticulum (ER) -Golgi intermediate compartment (ERGIC) and coat protein complex I (COPI) vesicles in some human cells. The encoded protein shares some homology with the yeast V-ATPase assembly factor Vma22p, and the orthologous protein in mouse promotes cell proliferation and suppresses cell death. Defects in this gene are a cause of congenital disorder of glycosylation, type IIo in humans.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Immunofluorescence: 5 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL
UniProt
Q96NT0
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human protein (amino acids M1-A180) was used as the immunogen for the CCDC115 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, IF, FACS, Direct ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the CCDC115 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This CCDC115 antibody is available for research use only.
Storage Conditions
After reconstitution, the CCDC115 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the CCDC115 antibody should be determined by the researcher.
Location
Cytoplasmic
Image Legend
IHC staining of FFPE human ovarian cancer tissue with CCDC115 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

UniProtKB · Q96NT0

Vacuolar ATPase assembly protein VMA22

VMA22_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q96NT0
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
VMA22
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B4DJ47, Q9BR88
Protein keywords

Coding sequence diversity

Alternative splicing

Domain

Coiled coil

Disease

Congenital disorder of glycosylationDisease variant

Cellular component

Cytoplasmic vesicleEndoplasmic reticulumEndosomeLysosome

Technical term

Proteomics identificationReference proteome
Product Datasheet
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