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CSF1R, Rat (HEK293, His, solution)

CAT: 0804-HY-P72955-01Size: 5 µgDry Ice: YesHazardous: No
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CAT#:0804-HY-P72955-01Size:5 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CSF1R Protein is a cell surface receptor with high a affinity for a variety of polypeptide growth factors, cytokines, and hormones. CSF1R Protein participate in PLCG2/PKA/UCP2 signaling pathway to reduce oxidative stress and neuronal apoptosis in rat models with neonatal HIE. The blocking of the CSF1R signal is associated with tumorigenesis. CSF1R Protein, Rat (HEK293, His, solution) is the recombinant rat-derived CSF1R protein, expressed by HEK293 , with C-His labeled tag.
Product Name Alternative
CSF1R Protein, Rat (HEK293, His, solution), Rat, HEK293
UNSPSC
12352202
Type
Recombinant Proteins
Assay Protocol
https://www.medchemexpress.com/cytokines/csf1r-protein-rat-hek293-his.html
Purity
96.90
Smiles
APVIEPSGPELVVEPGATVTLRCVSNGSVEWDGPISPYWTLDSESPGSILITKNATFKNTGTYRCTELEDPMRGSTAIHLYVKDPVRPWNLLAQEVTVFEGQEAVLPCLITDPTLKDSVSLVREWGRPVSRKTVYSFLPWRGFIIHKAKFLDSHTYMCKAVVNARESTSIGIRLKVNRAHPGPPHIILEPTKLVRIRGEAAQIVCSATHSEVEFNVILKRGDTKLEIPINSDFQDNAYKKVLTLNLNAVDFQDAGIYSCVANNAAGSNTATMNFQVVESAYLNLTSEQSLLQEVSVGENLDLTVIADAYPGLQRYNWTYLGPFFEDPHNLEFRTQWTTYSYSFKLHLNRVKPLEAGRYSLMAQNKAGWNNLTFELTLRYPPEVSVTWIPVNGSDVLLCDVSGYPQPNVTWMECRGHTDRCDEAQASQVWDDTQPEVLSQKPFHRVILQSQLPIGTLKHNMTYVCRAHNNVGNSSQFFRAISLGQSKQLPDE
Molecular Formula
307403 (Gene_ID) D4ACA7 (A64-E554) (Accession)
Molecular Weight
69-89 kDa
References & Citations
[1]Zwick E, et al. Receptor tyrosine kinase signalling as a target for cancer intervention strategies. Endocr Relat Cancer. 2001 Sep;8 (3) :161-73.|[2]Hu X, et al. Rh-CSF1 Attenuates Oxidative Stress and Neuronal Apoptosis via the CSF1R/PLCG2/PKA/UCP2 Signaling Pathway in a Rat Model of Neonatal HIE. Oxid Med Cell Longev. 2020 Oct 7;2020:6801587.|[3]Xu J, et al. CSF1R signaling blockade stanches tumor-infiltrating myeloid cells and improves the efficacy of radiotherapy in prostate cancer. Cancer Res. 2013 May 1;73 (9) :2782-94.|[4]Keshvari S, et al. CSF1R-dependent macrophages control postnatal somatic growth and organ maturation. PLoS Genet. 2021 Jun 3;17 (6) :e1009605.
Shipping Conditions
Dry ice
Storage Conditions
Stored at -80°C for 1 year
Scientific Category
Recombinant Proteins

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