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MHY884

CAT: 0804-HY-116145Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-116145Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MHY884 is a tyrosinase inhibitor that suppresses UVB-induced activation of NF-κB signaling pathway through the downregulation of oxidative stress. MHY884 suppresses oxidative stress in the melanoma cells and attenuates UVB-induced oxidative stress, resulting in reduced NF-κB activity in irradiated mice. MHY884 is promising for research of UVB-induced skin damage[1].
CAS Number
1393371-35-1
UNSPSC
12352005
Target
NF-κB; Tyrosinase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/mhy884.html
Smiles
OC1=C(OC)C=C(C2SC3=CC=C(Cl)C=C3N2)C=C1OC
Molecular Formula
C15H14ClNO3S
Molecular Weight
323.79
References & Citations
[1]Choi YJ, et al. MHY884, a newly synthesized tyrosinase inhibitor, suppresses UVB-induced activation of NF-κB signaling pathway through the downregulation of oxidative stress. Bioorg Med Chem Lett. 2014 Mar 1;24 (5) :1344-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
GTR19198876-01MHY884

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