C20 Sphingomyelin (d18:1/20:0)

C20 Sphingomyelin (d18:1/20:0)

• CAS Number: 121999-68-6
• UNSPSC Description: C20 Sphingomyelin (d18:1/20:0) (N-eicosanoyl-D-erythro-Sphingosylphosphorylcholine; SM(d18:1/20:0)) is a naturally occurring sphingolipid. C20 Sphingomyelin (d18:1/20:0) levels are upregulated in the hippocampus of streptozotocin (HY-13753)-induced diabetic rats and in human plasma, positively correlating with insulin resistance in obese humans. C20 Sphingomyelin (d18:1/20:0) is also upregulated in the liver of a mouse model of Niemann-Pick C1 disease, a neurodegenerative cholesterol sphingolipid lysosomal storage disorder.
• Target Antigen: Endogenous Metabolite
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: COVID-19-immunoregulation
• Field of Research: Endocrinology
• Assay Protocol: https://www.medchemexpress.com/c20-sphingomyelin-d18-1-20-0.html
• Smiles: CCCCCCCCCCCCCCCCCCCC(N[C@H]([C@H](O)/C=C/CCCCCCCCCCCCC)COP(OCC[N+](C)(C)C)([O-])=O)=O
• Molecular Weight: 759.13
• References & Citations: [1]Hanamatsu, et al. Altered levels of serum sphingomyelin and ceramide containing distinct acyl chains in young obese adults. Nutr. Diabetes 4(10), e141 (2014).
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported