Recombinant Mouse Steroidogenic factor 1 (Nr5a1)

Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Dry Ice Shipment: No

Alternative Products

Cat	Name
MBS7115510-03	Recombinant Mouse Steroidogenic factor 1 (Nr5a1)
MBS7115510-02	Recombinant Mouse Steroidogenic factor 1 (Nr5a1)
MBS7115510-01	Recombinant Mouse Steroidogenic factor 1 (Nr5a1)
MBS962773-05	Recombinant Mouse Steroidogenic factor 1 (Nr5a1), partial
MBS962773-02	Recombinant Mouse Steroidogenic factor 1 (Nr5a1), partial
MBS962773-03	Recombinant Mouse Steroidogenic factor 1 (Nr5a1), partial
MBS962773-04	Recombinant Mouse Steroidogenic factor 1 (Nr5a1), partial
MBS962773-01	Recombinant Mouse Steroidogenic factor 1 (Nr5a1), partial
MBS046090-01	Mouse Steroidogenic Factor 1 ELISA Kit
MBS046090-03	Mouse Steroidogenic Factor 1 ELISA Kit

CAT:

399-CSB-CF016065MO-02

Size:

20 µg

Price:

Ask

For price, please contact [email protected].

Recombinant Mouse Steroidogenic factor 1 (Nr5a1)

Gene Name: Nr5a1
UniProt: P33242
Expression Region: 1-462aa
Organism: Mus musculus
Target Sequence: MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKLETGPPMGVPPPPPPPPDYMLPPSLHAPEPKALVSGPPSGPLGDFGAPSLPMAVPGPHGPLAGYLYPAFSNRTIKSEYPEPYASPPQQPGPPYSYPEPFSGGPNVPELILQLLQLEPEEDQVRARIVGCLQEPAKSRSDQPAPFSLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVLDHIYRQVQYGKEDSILLVTGQEVELSTVAVQAGSLLHSLVLRAQELVLQLHALQLDRQEFVCLKFLILFSLDVKFLNNHSLVKDAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT
Tag: N-terminal 6xHis-tagged
Source: in vitro E.coli expression system
Field of Research: Developmental Biology
Assay Type: Developed Protein
Relevance: Transcriptional activator. Seems to be essential for sexual differentiation and formation of the primary steroidogenic tissues. Binds to the Ad4 site found in the promoter region of steroidogenic P450 genes such as CYP11A, CYP11B and CYP21B. Also regulates the AMH/Muellerian inhibiting substance gene as well as the AHCH and STAR genes. 5'-YCAAGGYC-3' and 5'-RRAGGTCA-3' are the consensus sequences for the recognition by NR5A1. The SFPQ-NONO-NR5A1 complex binds to the CYP17 promoter and regulates basal and cAMP-dependent transcriptional activity . Transcription repressor of the Moloney leukemia virus long terminal repeat in undifferentiated murine embryonal carcinoma cells. Binds phosphatidylcholine and phospholipids with a phosphatidylinositol headgroup, in particular phosphatidylbisphosphate, phosphatidylbisphosphate and phosphatidyltriphosphate. Activated by the phosphorylation of NR5A1 by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.
Purity: Greater than 85% as determined by SDS-PAGE.
Activity: Not Test
Length: Full Length
Form: Liquid or Lyophilized powder
Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Molecular Weight: 58.0 kDa
References & Citations: "Cyclic AMP stimulates SF-1-dependent CYP11A1 expression through homeodomain-interacting protein kinase 3-mediated Jun N-terminal kinase and c-Jun phosphorylation." Lan H.-C., Li H.-J., Lin G., Lai P.-Y., Chung B.-C. Mol. Cell. Biol. 27:2027-2036 (2007)
Storage Conditions: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.

Complementary Product Range

Our range of products, including Recombinant Mouse Steroidogenic factor 1 (Nr5a1), falls within the same field of application and can be used across various research projects. These products are carefully selected for their high performance and reliability, supporting the diverse needs of modern laboratories. Whether for ongoing studies or future experiments, they are designed to help researchers achieve their scientific goals. Here are some related products that may be of interest for similar or future applications:

Each item in our collection, is tested for precision and quality, ensuring dependable solutions for your research. As we continue to incorporate the latest advancements, Gentaur ensures that our product range remains relevant and versatile, providing you with the tools needed for both current and future projects.

Find us on

Cat	Name
CSB-CF016065MO-01	Recombinant Mouse Steroidogenic factor 1 (Nr5a1)
CSB-CF016065MO-02	Recombinant Mouse Steroidogenic factor 1 (Nr5a1)
CSB-CF623795HU(A4)-01	Recombinant Human Steroidogenic factor 1 (NR5A1)
CSB-CF623795HU(A4)-02	Recombinant Human Steroidogenic factor 1 (NR5A1)
CSB-EP623795HU-03	Recombinant Human Steroidogenic factor 1 (NR5A1), partial
CSB-EP623795HU-02	Recombinant Human Steroidogenic factor 1 (NR5A1), partial
CSB-EP623795HU-01	Recombinant Human Steroidogenic factor 1 (NR5A1), partial
CSB-YP025270MO-03	Recombinant Mouse Transthyretin (Ttr)
CSB-YP016264MO-01	Recombinant Mouse Oncomodulin (Ocm)
CSB-YP013529MO-03	Recombinant Mouse Myoglobin (Mb)