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Oxatomide (Standard)

CAT: 0804-HY-123205R-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-123205R-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Oxatomide (Standard) (KW-4354 (Standard) ) is the analytical standard of Oxatomide. This product is intended for research and analytical applications. Oxatomide (KW-4354) is an orally active dual antagonist of the H1-histamine receptor and the P2X7 receptor, as well as an inhibitor of serotonin. Oxatomide possesses antihistaminic, antiallergic and anti-inflammatory activities. Oxatomide can be used in the research of allergic diseases[1][2].
CAS Number
60607-34-3
Product Name Alternative
KW-4354 (Standard)
UNSPSC
12352005
Target
5-HT Receptor; Apoptosis; COX; Histamine Receptor; P2X Receptor; p38 MAPK; PERK; Reference Standards
Type
Reference Standards
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; GPCR/G Protein; Immunology/Inflammation; MAPK/ERK Pathway; Membrane Transporter/Ion Channel; Neuronal Signaling; Others
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/oxatomide-standard.html
Smiles
O=C1NC2=CC=CC=C2N1CCCN3CCN(CC3)C(C4=CC=CC=C4)C5=CC=CC=C5
Molecular Formula
C27H30N4O
Molecular Weight
426.55
References & Citations
[1] Kazuki Yoshida, et al. P2X7 receptor antagonist activity of the anti-allergic agent oxatomide. Eur J Pharmacol. 2015 Nov 15;767:41-51.|[2]K Ohmori, et al. Pharmacological studies on oxatomide (KW-4354) . (7) Antagonistic effects on chemical mediators. Nihon Yakurigaku Zasshi. 1983 May;81 (5) :399-409.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Clinical Information
No Development Reported

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