CTPS1-IN-2

• UNSPSC Description:

  CTPS1-IN-2 (P115) is an inhibitor of Cytidine Triphosphate Synthase 1 (CTPS1) with an IC50 value of ≤ 0.1 μM. CTPS1-IN-2 can be used for research on cancer (such as leukemia and lymphoma), inflammatory skin diseases (such as psoriasis), or multiple sclerosis[1].

• Target Antigen:

  DNA/RNA Synthesis

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Cancer; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/ctps1-in-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1(CCOCC1)C2=NC(NS(=O)(C3CC3)=O)=NC=C2)NC4=NC=C(C5=CN=CC(OCC)=N5)C=C4

• Molecular Weight:

  525.58

• References & Citations:

  [1]Quddus, et al. "N-(4-(5-chloropyridin-3-yl) phenyl)-2-(2-(cyclopropanesulfonamido) pyrimidin-4-yl) butanamide derivatives and related compounds as human CTPS1 inhibitors for the treatment of proliferative diseases." U.S. Patent. WO2019179652 A1. 2023-03-23

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2377000-84-3