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Ancitabine

CAT: 0804-HY-N0093ASize: 1 EachDry Ice: NoHazardous: No
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ancitabine is the precursor of the anticancer agent Cytarabine , which targets targets related to cell metabolism and proliferation. Ancitabine can inhibit tumor cell proliferation, interfere with the DNA synthesis process of tumor cells, and prevent cell division. Under alkaline pH conditions, Ancitabine can be quantitatively converted into Cytarabine and can be used in the study of cancers such as colorectal cancer[1][2].
CAS Number
31698-14-3
Product Name Alternative
Cyclocytidine; Cyclo-CMP
UNSPSC
12352005
Hazard Statement
H315-H319-H320
Target
Autophagy; CMV; DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Anti-infection; Autophagy; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ancitabine.html
Solubility
10 mM in DMSO
Smiles
OC[C@@H]1[C@@H](O)[C@@](O2)([H])[C@@](N(C2=N3)C=CC3=N)([H])O1
Molecular Formula
C9H11N3O4
Molecular Weight
225.20
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1]Aftab O, et al. Detection of cell aggregation and altered cell viability by automated label-free video microscopy: a promising alternative to endpoint viability assays in high-throughput screening. J Biomol Screen. 2015 Mar;20 (3) :372-81.|[2]Kirsch LE, et al. Aqueous conversion kinetics and mechanisms of ancitabine, a prodrug of the antileukemic agent cytarabine. J Pharm Sci. 1984 Jul;73 (7) :896-902.x
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched

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