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Crenigacestat

CAT: 0026-B3255-5Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0026-B3255-5Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Crenigacestat (LY3039478), is a potent Notch inhibitor with an IC50 of ~1nM in most of the tumor cell lines tested. LY3039478 potently inhibits mutant Notch receptor activity. In a xenograft tumor model, LY3039478 inhibited N1ICD cleavage and expression of Notch-regulated genes in the tumor microenvironment
Shipping Conditions
Gel Pack
Storage Conditions
-20ºC
Shelf Life
36 months

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