LRE1

• Description :

  LRE1 is a specific and allosteric inhibitor of soluble adenylyl cyclase.

• CAS Number :

  [1252362-53-0]

• UNSPSC :

  12352005

• Hazard Statement :

  H315, H319

• Target :

  Adenylate Cyclase

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/LRE1.html

• Purity :

  99.91

• Solubility :

  DMSO : 125 mg/mL (ultrasonic)

• Smiles :

  NC1=NC(N(CC2=CC=CS2)C3CC3)=CC(Cl)=N1

• Molecular Formula :

  C12H13ClN4S

• Molecular Weight :

  280.78

• Precautions :

  H315, H319

• References & Citations :

  [1]Ramos-Espiritu L, et al. Discovery of LRE1 as a specific and allosteric inhibitor of soluble adenylyl cyclase. Nat Chem Biol. 2016 Oct;12 (10) :838-44.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported